About Calcium Folinate (Leucovorin Calcium)
Class: | Antidote, Chemoprotective Agent
Use: | Used to reduce the toxicity of methotrexate, to treat folate deficiency, and as an adjunct in the treatment of certain types of cancer (e.g., colorectal cancer)
Adult dose: | Typically 15 mg to 30 mg administered intramuscularly or intravenously, depending on the indication and treatment protocol
Pediatric dose: | 0.5 mg to 1 mg/kg body weight, administered intravenously or intramuscularly, with a maximum dose of 15 mg
Side effects: | Commo
Drug Class
Antidote, Chemoprotective Agent
Uses & Indications
Used to reduce the toxicity of methotrexate, to treat folate deficiency, and as an adjunct in the treatment of certain types of cancer (e.g., colorectal cancer)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light and do not freeze
Manufacturer & Packaging
Manufacturer: Ebewe Pharma Ges. m.b.H MFG. KG, AUSTRIA
Package Size
10ml Vial
Price & Supplier
Price in UAE: AED 54.50
Dosage Information
Adult Dose
Typically 15 mg to 30 mg administered intramuscularly or intravenously, depending on the indication and treatment protocol
Pediatric Dose
0.5 mg to 1 mg/kg body weight, administered intravenously or intramuscularly, with a maximum dose of 15 mg
Side Effects
Common side effects include nausea, vomiting, diarrhea, and allergic reactions such as rash or itching
Contraindications & Precautions
Hypersensitivity to leucovorin or any component of the formulation; should not be used in patients with pernicious anemia or other megaloblastic anemias due to vitamin B12 deficiency
Important Warnings
Monitor for signs of hypersensitivity; use caution in patients with renal impairment; may interfere with the effects of certain antineoplastic agents; not a substitute for folic acid in patients with folate deficiency due to malabsorption or other underlying conditions
Related Medicines in Same Category
See also: Other Antidote, Chemoprotective Agent medicines available in UAE pharmacies
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Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.